Zhou B. Antioxidative, anti-inflammatory and anti-apoptotic effects of ellagic acid in liver and brain of rats treated by D-galactose. The ellagitannins (ellagic acids) are metabolised to urolithins that are circulated in the plasma of consumers, thereby increasing the counts of bifidobacteria and lactobacilli. The ellagic acid metabolites urolithin A and B differentially affect growth, adhesion, motility, and invasion of endometriotic cells in vitro. Espn JC, Larrosa M, Garca-Conesa MT, et al. . Food Chem Toxicol 108: 289297, 2017. doi: 10.1016/j.fct.2017.07.050. It belongs to the class of organic compounds known as benzo-coumarins or dibenzo--pyrones.Its precursors ellagic acids and ellagitannins are ubiquitous in nature, including edible plants, such as pomegranates, strawberries, raspberries, and walnuts. Urolithin A, a metabolite compound resulting from the transformation of ellagitannins by gut bacteria, has been reported to have anti-oxidant, anti-inflammatory, and anti-apoptotic properties. Ellagic acid attenuates beryllium sulphate-induced oxidative stress and histopathological alterations of spleen in rats. Studies suggest that the ellagic acid-rich fractions and metabolites of pomegranate urolithin-A provide a protective effect against colitis . Ellagic acid attenuates beryllium sulphate-induced oxidative stress and histopathological alterations of spleen in rats. Pages: 1047-1054. This mechanism led us to test Urolithin A, a common metabolite that promotes mitophagy and extends lifespan in C. elegans, as a possible therapeutic to delay reproductive decline. Zhou B. Antioxidative, anti-inflammatory and anti-apoptotic effects of ellagic acid in liver and brain of rats treated by D-galactose. (1) Background: Ellagic acid (EA) acts as a product of gut microbiota transformation to prevent insulin resistance, which is limited by high-fat diet (HFD)-induced dysbiosis. Zhou B. Antioxidative, anti-inflammatory and anti-apoptotic effects of ellagic acid in liver and brain of rats treated by D-galactose. Taninos hidrolizables; bioqumica, aspectos nutricionales y analticos y efectos en la salud. Revisin. Hum Reprod. 9 , 41004106 (2018). This mechanism led us to test Urolithin A, a common metabolite that promotes mitophagy and extends lifespan in C. elegans, as a possible therapeutic to delay reproductive decline. Revisin. Francisco Javier Olivas-Aguirre 1, Abraham Wall-Medrano 1, Gustavo A. Gonzlez-Aguilar 2, . Another dietary polyphenol such as ellagic acid and ellagitannins are transformed into urolithin A (an anti-inflammatory metabolite) by Gordonibacter spp. Pomegranate is a tree. 2015;31(1):55-66 ISSN 0212-1611 CODEN NUHOEQ S.V.R. show that Urolithin A, a natural metabolite of pomegranate extract, enhances antigen presentation in cancer and promotes mitophagy in CD8+ T cells, resulting in generation regenerative stem cell-like memory (TSCM) cells with enhanced anti-tumor properties. Crossref | PubMed | ISI | Google Scholar; 22. Yuandi Lei, Tianyi Jiang, Liqin He, Yanping Liu, Zhanbing Sun, Weihua Deng, Lian Huang & Zhaohui Zhang. 318. . According to a tissue distribution experiment in wild-type mice, the prostate gland rapidly takes up high concentrations of UA after oral or intraperitoneal administration (0.3 mg/mouse/dose). Francisco Javier Olivas-Aguirre 1, Abraham Wall-Medrano 1, Gustavo A. Gonzlez-Aguilar 2, . Thus, urolithin A, the end-products of both ellagitannins and ellagic acid, extends lifespan and improves fitness during C. elegans aging and improves muscle function and exercise capacity in rodents. 2015;31(1):55-66 ISSN 0212-1611 CODEN NUHOEQ S.V.R. Various parts of the tree and fruit are used to make medicine. . . (1) Background: Ellagic acid (EA) acts as a product of gut microbiota transformation to prevent insulin resistance, which is limited by high-fat diet (HFD)-induced dysbiosis. Thus, urolithin A, the end-products of both ellagitannins and ellagic acid, extends lifespan and improves fitness during C. elegans aging and improves muscle function and exercise capacity in rodents. Espn JC, Larrosa M, Garca-Conesa MT, Toms-Barbern F. Article PubMed Google Scholar show that Urolithin A, a natural metabolite of pomegranate extract, enhances antigen presentation in cancer and promotes mitophagy in CD8+ T cells, resulting in generation regenerative stem cell-like memory (TSCM) cells with enhanced anti-tumor properties. Article Google Scholar Food Chem Toxicol 108: 289297, 2017. doi: 10.1016/j.fct.2017.07.050. Francisco Javier Olivas-Aguirre 1, Abraham Wall-Medrano 1, Gustavo A. Gonzlez-Aguilar 2, . 9 , 41004106 (2018). The ellagic acid metabolites urolithin A and B differentially affect growth, adhesion, motility, and invasion of endometriotic cells in vitro. (1) Background: Ellagic acid (EA) acts as a product of gut microbiota transformation to prevent insulin resistance, which is limited by high-fat diet (HFD)-induced dysbiosis. Among the various metabolites, Urolithin-A was found to be more dynamic by hindering the synthesis of Ellagitannins (the main polyphenols in pomegranate juice) are hydrolyzed to ellagic acid, and then to urolithin A (UA) derivatives. Among the various metabolites, Urolithin-A was found to be more dynamic by hindering the synthesis of Studies suggest that the ellagic acid-rich fractions and metabolites of pomegranate urolithin-A provide a protective effect against colitis . The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging. In-depth analysis demonstrates that mitophagy is required for the beneficial effect of urolithin A (Ryu et al., 2016). Various parts of the tree and fruit are used to make medicine. Crossref | PubMed | ISI | Google Scholar; 22. Pomegranate is a tree. Published online: 01 Jun 2022. Food Funct. In our trial, elevated urolithin A was correlated with walnut and Mankai consumption, as its precursor, ellagic acid , was found in both. Taninos hidrolizables; bioqumica, aspectos nutricionales y analticos y efectos en la salud. Zhi-hao Yu, Mei Cao, Yuan-xiao Wang, Shi-ying Yan, Li-ting Qing, Cheng-meng Wu, Shu Li lncRNA MPFAST Promotes Proliferation and Fatty Acid Synthesis of Bovine Mammary Epithelial Cell by Sponging miR-103 Regulating PI3K-AKT Pathway. . The ellagic acid metabolites urolithin A and B differentially affect growth, adhesion, motility, and invasion of endometriotic cells in vitro. The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging. [ 70 ]. Mc Cormack B, Maenhoudt N, Fincke V, Stejskalova A, Greve B, Kiesel L, et al. Anti-tumor immunity is limited by reduced T cell persistence and antigen presentation. It belongs to the class of organic compounds known as benzo-coumarins or dibenzo--pyrones.Its precursors ellagic acids and ellagitannins are ubiquitous in nature, including edible plants, such as pomegranates, strawberries, raspberries, and walnuts. Ellagitannins (the main polyphenols in pomegranate juice) are hydrolyzed to ellagic acid, and then to urolithin A (UA) derivatives. Espn JC, Larrosa M, Garca-Conesa MT, Toms-Barbern F. Polyphenols can also detoxify gut metabolites and repress the growth of pathogenic bacteria, such as Clostridium perfringens, Clostridium difficile and Bacteroides spp. Taninos hidrolizables; bioqumica, aspectos nutricionales y analticos y efectos en la salud. Jose Alberto Lpez-Daz 1, Emilio lvarez-Parrilla 1, Laura A. de la Rosa 1 y Arnulfo Ramos-Jimenez 1 Urolithin A Attenuates Helicobacter pylori-Induced Damage In Vivo. Zhi-hao Yu, Mei Cao, Yuan-xiao Wang, Shi-ying Yan, Li-ting Qing, Cheng-meng Wu, Shu Li lncRNA MPFAST Promotes Proliferation and Fatty Acid Synthesis of Bovine Mammary Epithelial Cell by Sponging miR-103 Regulating PI3K-AKT Pathway. Crossref | PubMed | ISI | Google Scholar; 22. Polyphenols can also detoxify gut metabolites and repress the growth of pathogenic bacteria, such as Clostridium perfringens, Clostridium difficile and Bacteroides spp. Hum Reprod. Crossref | PubMed | ISI | Google Scholar; 22. Ellagitannins (the main polyphenols in pomegranate juice) are hydrolyzed to ellagic acid, and then to urolithin A (UA) derivatives. [ 70 ]. 318. Interestingly, Phoenix dactylifera extract (including gallic acid, coffeic acid, and ellagic acid phytochemicals) increased cardiac and kidney PD-1 expressions in a mouse model exposed to Adriamycin . Crossref | PubMed | ISI | Google Scholar; 22. Safety assessment of urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid. Studies suggest that the ellagic acid-rich fractions and metabolites of pomegranate urolithin-A provide a protective effect against colitis . Safety assessment of urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid. Food Funct. show that Urolithin A, a natural metabolite of pomegranate extract, enhances antigen presentation in cancer and promotes mitophagy in CD8+ T cells, resulting in generation regenerative stem cell-like memory (TSCM) cells with enhanced anti-tumor properties. In addition, plasma hippuric acid, a glycine conjugate of benzoic acid, both metabolites present in Mankai, was significantly associated with VAT reduction even after controlling for WC change. It is a type of phenolic compound that is produced in the human gut after absorption of ellagitannin containing foods such as pomegranate, strawberries, Denk et al. . Zhi-hao Yu, Mei Cao, Yuan-xiao Wang, Shi-ying Yan, Li-ting Qing, Cheng-meng Wu, Shu Li lncRNA MPFAST Promotes Proliferation and Fatty Acid Synthesis of Bovine Mammary Epithelial Cell by Sponging miR-103 Regulating PI3K-AKT Pathway. Another dietary polyphenol such as ellagic acid and ellagitannins are transformed into urolithin A (an anti-inflammatory metabolite) by Gordonibacter spp. Urolithin A Attenuates Helicobacter pylori-Induced Damage In Vivo. Denk et al. Nutr Hosp. Urolithin A is a metabolite compound resulting from the transformation of ellagitannins by the gut bacteria. It is a type of phenolic compound that is produced in the human gut after absorption of ellagitannin containing foods such as pomegranate, strawberries, The aim of this study was to investigate the synergistic effects and mechanisms of supplementation with the probiotic Weizmannia coagulans (W. coagulans) on the prevention of insulin resistance by EA; Espn JC, Larrosa M, Garca-Conesa MT, Toms-Barbern F. The ellagitannins (ellagic acids) are metabolised to urolithins that are circulated in the plasma of consumers, thereby increasing the counts of bifidobacteria and lactobacilli. 9 , 41004106 (2018). In our trial, elevated urolithin A was correlated with walnut and Mankai consumption, as its precursor, ellagic acid , was found in both. Urolithin A is a metabolite compound resulting from the transformation of ellagitannins by the gut bacteria. Food Funct. Urolithin A Attenuates Helicobacter pylori-Induced Damage In Vivo. Pomegranate is a tree. Mc Cormack B, Maenhoudt N, Fincke V, Stejskalova A, Greve B, Kiesel L, et al. Espn JC, Larrosa M, Garca-Conesa MT, Toms-Barbern F. Pages: 1047-1054. In addition, plasma hippuric acid, a glycine conjugate of benzoic acid, both metabolites present in Mankai, was significantly associated with VAT reduction even after controlling for WC change. In-depth analysis demonstrates that mitophagy is required for the beneficial effect of urolithin A (Ryu et al., 2016). . According to a tissue distribution experiment in wild-type mice, the prostate gland rapidly takes up high concentrations of UA after oral or intraperitoneal administration (0.3 mg/mouse/dose). Mc Cormack B, Maenhoudt N, Fincke V, Stejskalova A, Greve B, Kiesel L, et al. Espn JC, Larrosa M, Garca-Conesa MT, et al. Interestingly, Phoenix dactylifera extract (including gallic acid, coffeic acid, and ellagic acid phytochemicals) increased cardiac and kidney PD-1 expressions in a mouse model exposed to Adriamycin . Thus, urolithin A, the end-products of both ellagitannins and ellagic acid, extends lifespan and improves fitness during C. elegans aging and improves muscle function and exercise capacity in rodents. Espn JC, Larrosa M, Garca-Conesa MT, Toms-Barbern F. In our trial, elevated urolithin A was correlated with walnut and Mankai consumption, as its precursor, ellagic acid , was found in both. Urolithin B is one of the four metabolites of the Ellagic Acid/Ellagitannins family. Safety assessment of urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid. Crossref | PubMed | ISI | Google Scholar; 22. This mechanism led us to test Urolithin A, a common metabolite that promotes mitophagy and extends lifespan in C. elegans, as a possible therapeutic to delay reproductive decline. 2021;36:150119. 318. Published online: 01 Jun 2022. The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging. . Espn JC, Larrosa M, Garca-Conesa MT, et al. The Phoenix dactylifera extract led to attenuated cardiotoxicity and nephrotoxicity secondary to decreased oxidative stress and apoptotic pressure. Urolithin B is one of the four metabolites of the Ellagic Acid/Ellagitannins family. Food Chem Toxicol 108: 289297, 2017. doi: 10.1016/j.fct.2017.07.050. It is a type of phenolic compound that is produced in the human gut after absorption of ellagitannin containing foods such as pomegranate, strawberries, The aim of this study was to investigate the synergistic effects and mechanisms of supplementation with the probiotic Weizmannia coagulans (W. coagulans) on the prevention of insulin resistance by EA; Article PubMed Google Scholar Published online: 01 Jun 2022. In-depth analysis demonstrates that mitophagy is required for the beneficial effect of urolithin A (Ryu et al., 2016). The aim of this study was to investigate the synergistic effects and mechanisms of supplementation with the probiotic Weizmannia coagulans (W. coagulans) on the prevention of insulin resistance by EA; Denk et al. Urolithin A is a metabolite compound resulting from the transformation of ellagitannins by the gut bacteria. It belongs to the class of organic compounds known as benzo-coumarins or dibenzo--pyrones.Its precursors ellagic acids and ellagitannins are ubiquitous in nature, including edible plants, such as pomegranates, strawberries, raspberries, and walnuts. Yuandi Lei, Tianyi Jiang, Liqin He, Yanping Liu, Zhanbing Sun, Weihua Deng, Lian Huang & Zhaohui Zhang. Nutr Hosp. Among the various metabolites, Urolithin-A was found to be more dynamic by hindering the synthesis of Interestingly, Phoenix dactylifera extract (including gallic acid, coffeic acid, and ellagic acid phytochemicals) increased cardiac and kidney PD-1 expressions in a mouse model exposed to Adriamycin . The ellagitannins (ellagic acids) are metabolised to urolithins that are circulated in the plasma of consumers, thereby increasing the counts of bifidobacteria and lactobacilli. Revisin. Hum Reprod. Urolithin A, a metabolite compound resulting from the transformation of ellagitannins by gut bacteria, has been reported to have anti-oxidant, anti-inflammatory, and anti-apoptotic properties. Nutr Hosp. The Phoenix dactylifera extract led to attenuated cardiotoxicity and nephrotoxicity secondary to decreased oxidative stress and apoptotic pressure. Article Google Scholar Urolithin B is one of the four metabolites of the Ellagic Acid/Ellagitannins family. Safety assessment of urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid. Safety assessment of urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid. Food Chem Toxicol 108: 289297, 2017. doi: 10.1016/j.fct.2017.07.050. Anti-tumor immunity is limited by reduced T cell persistence and antigen presentation. Anti-tumor immunity is limited by reduced T cell persistence and antigen presentation. Article Google Scholar In addition, plasma hippuric acid, a glycine conjugate of benzoic acid, both metabolites present in Mankai, was significantly associated with VAT reduction even after controlling for WC change. Safety assessment of urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid. Food Chem Toxicol 108: 289297, 2017. doi: 10.1016/j.fct.2017.07.050. 2015;31(1):55-66 ISSN 0212-1611 CODEN NUHOEQ S.V.R. [ 70 ]. 2021;36:150119. Another dietary polyphenol such as ellagic acid and ellagitannins are transformed into urolithin A (an anti-inflammatory metabolite) by Gordonibacter spp. Various parts of the tree and fruit are used to make medicine. The Phoenix dactylifera extract led to attenuated cardiotoxicity and nephrotoxicity secondary to decreased oxidative stress and apoptotic pressure. Polyphenols can also detoxify gut metabolites and repress the growth of pathogenic bacteria, such as Clostridium perfringens, Clostridium difficile and Bacteroides spp. . Ellagic acid attenuates beryllium sulphate-induced oxidative stress and histopathological alterations of spleen in rats. Food Chem Toxicol 108: 289297, 2017. doi: 10.1016/j.fct.2017.07.050. 2021;36:150119. Pages: 1047-1054. Yuandi Lei, Tianyi Jiang, Liqin He, Yanping Liu, Zhanbing Sun, Weihua Deng, Lian Huang & Zhaohui Zhang. Urolithin A, a metabolite compound resulting from the transformation of ellagitannins by gut bacteria, has been reported to have anti-oxidant, anti-inflammatory, and anti-apoptotic properties. Jose Alberto Lpez-Daz 1, Emilio lvarez-Parrilla 1, Laura A. de la Rosa 1 y Arnulfo Ramos-Jimenez 1 Espn JC, Larrosa M, Garca-Conesa MT, Toms-Barbern F. Jose Alberto Lpez-Daz 1, Emilio lvarez-Parrilla 1, Laura A. de la Rosa 1 y Arnulfo Ramos-Jimenez 1 According to a tissue distribution experiment in wild-type mice, the prostate gland rapidly takes up high concentrations of UA after oral or intraperitoneal administration (0.3 mg/mouse/dose). Article PubMed Google Scholar